John Pham was born in Saigon and subsequently raised in the United States. He received a self publishing grant from the Xeric Foundation in 2000 for "Epoxy." His Sublife #2 from Fantagraphics Books was nominated for an Outstanding Artist, Outstanding Series, and Outstanding Comic at the 2010 Ignatz Awards and an excerpt from Sublife was anthologized in The Best American Comics 2010, edited by Neil Gaiman. He was interviewed in issue 259 of The Comics Journal. He also contributed a story to volume 7 of the acclaimed anthology, Kramers Ergot. He worked on the Cartoon Network series, Problem Solverz for much of 2011, and was included in The Best American Comics 2011 anthology, edited by Alison Bechdel. That year, he was also a featured international guest (representing the US) at the Angouleme comics festival in France.